2kw3

Solution NMR

Heterotrimeric interaction between RFX5 and RFXAP

Released:
Source organism: Homo sapiens
Entry authors: Laird KM, Briggs LL, Boss JM, Summers MF, Garvie CW

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-126226 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA-binding protein RFX5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 68 amino acids
Theoretical weight: 7.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P48382 (Residues: 24-90; Coverage: 11%)
Gene name: RFX5
Sequence domains: RFX5 N-terminal domain
Structure domains: Helix Hairpins
Regulatory factor X-associated protein Chain: C
Molecule details ›
Chain: C
Length: 62 amino acids
Theoretical weight: 7.09 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O00287 (Residues: 214-272; Coverage: 22%)
Gene name: RFXAP
Sequence domains: Regulatory factor X-associated C-terminal binding domain
Structure domains: Regulatory factor X-associated C-terminal binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Not provided