› 2kwc

Solution NMR

The NMR structure of the autophagy-related protein Atg8

Released:
DOI: 10.2210/pdb2kwc/pdb
PDB entry 2kwc coloured by chain, ensemble of 20 models, front view.
PDB entry 2kwc coloured by chain, ensemble of 20 models, side view.
PDB entry 2kwc coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The NMR structure of the autophagy-related protein Atg8.
Kumeta H, Watanabe M, Nakatogawa H, Yamaguchi M, Ogura K, Adachi W, Fujioka Y, Noda NN, Ohsumi Y, Inagaki F
J Biomol NMR 47 237-41 (2010)
PMID: 20428927

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153570 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Autophagy-related protein 8 Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 13.46 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P38182 (Residues: 1-116; Coverage: 99%)
Gene names: APG8, ATG8, AUT7, CVT5, YBL0732, YBL078C
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Mammalian Autophagy: How Does It Work?
Bento et al. (2016)
11 more

5 mentions without citation

Substrate specificity of the ubiquitin and Ubl proteases.
Ronau et al. (2016)
4 more