› 2kxl

Solution NMR

Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state

Released:
DOI: 10.2210/pdb2kxl/pdb
PDB entry 2kxl coloured by chain, ensemble of 15 models, front view.
PDB entry 2kxl coloured by chain, ensemble of 15 models, side view.
PDB entry 2kxl coloured by chain, ensemble of 15 models, top view.
Source organism: Mesorhizobium loti
Primary publication:
Structural insights into conformational changes of a cyclic nucleotide-binding domain in solution from Mesorhizobium loti K1 channel.
Schünke S, Stoldt M, Lecher J, Kaupp UB, Willbold D
Proc Natl Acad Sci U S A 108 6121-6 (2011)
PMID: 21430265

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cyclic nucleotide-gated potassium channel mll3241 Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 14.98 KDa
Source organism: Mesorhizobium loti
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q98GN8 (Residues: 216-355; Coverage: 39%)
Gene name: mll3241
Sequence domains: Cyclic nucleotide-binding domain
Structure domains: Jelly Rolls

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

CNG channel structure, function, and gating: a tale of conformational flexibility.
Napolitano et al. (2021)
29 other articles

6 mentions without citation

Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Kowal et al. (2014)
5 more