2kxw

Solution NMR

Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138170 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 8.42 KDa
Source organism: Paramecium tetraurelia
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07463 (Residues: 77-149; Coverage: 49%)
Gene names: CAM, GSPATT00015825001
Sequence domains: EF-hand domain pair
Sodium channel protein type 2 subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 27 amino acids
Theoretical weight: 3.37 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P04775 (Residues: 1901-1927; Coverage: 1%)
Gene names: Scn2a, Scn2a1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided