› 2ky3

Solution NMR

Solution structure of GS-alfa-Ktx5.4 synthetic scorpion like

Released:
DOI: 10.2210/pdb2ky3/pdb
PDB entry 2ky3 coloured by chain, ensemble of 17 models, front view.
PDB entry 2ky3 coloured by chain, ensemble of 17 models, side view.
PDB entry 2ky3 coloured by chain, ensemble of 17 models, top view.
Source organism: Mesobuthus tamulus
Primary publication:
Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines.
Ramírez-Cordero B, Toledano Y, Cano-Sánchez P, Hernández-López R, Flores-Solis D, Saucedo-Yáñez AL, Chávez-Uribe I, Brieba LG, del Río-Portilla F
Chem Res Toxicol 27 960-7 (2014)
PMID: 24821061

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 5.4 Chain: A
Molecule details ›
Chain: A
Length: 33 amino acids
Theoretical weight: 3.61 KDa
Source organism: Mesobuthus tamulus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P59869 (Residues: 1-31; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 49%
Refinement method: TORSION ANGLE DYNAMICS, MOLECULAR DYNAMICS
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Voltage-Gated K+/Na+ Channels and Scorpion Venom Toxins in Cancer.
Díaz-García et al. (2020)
2 more