2l2k

Solution NMR

Solution NMR structure of the R/G STEM LOOP RNA-ADAR2 DSRBM2 Complex

Released:

Function and Biology Details

Reaction catalysed:
Adenine in double-stranded RNA + H(2)O = hypoxanthine in double-stranded RNA + NH(3)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-187626 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Double-stranded RNA-specific editase 1 Chain: B
Molecule details ›
Chain: B
Length: 71 amino acids
Theoretical weight: 7.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q91ZS8 (Residues: 231-301; Coverage: 10%)
Gene names: Adar2, Adarb1, Red1
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain
RNA (42-MER) Chain: A
Molecule details ›
Chain: A
Length: 42 nucleotides
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided