› 2l37

Solution NMR

3D solution structure of arginine/glutamate-rich polypeptide Luffin P1 from the seeds of sponge gourd (Luffa cylindrical)

Released:
DOI: 10.2210/pdb2l37/pdb
PDB entry 2l37 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l37 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l37 coloured by chain, ensemble of 20 models, top view.
Source organism: Luffa aegyptiaca
Primary publication:
Structural characterization and anti-HIV-1 activities of arginine/glutamate-rich polypeptide Luffin P1 from the seeds of sponge gourd (Luffa cylindrica).
Ng YM, Yang Y, Sze KH, Zhang X, Zheng YT, Shaw PC
J Struct Biol 174 164-72 (2011)
PMID: 21195767

Function and Biology Details

Reaction catalysed: 
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157496 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribosome-inactivating protein luffin P1 Chain: A
Molecule details ›
Chain: A
Length: 43 amino acids
Theoretical weight: 5.24 KDa
Source organism: Luffa aegyptiaca
Expression system: Escherichia coli
UniProt:
  • Canonical: P56568 (Residues: 3-45; Coverage: 92%)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Antimicrobial Peptides from Plants.
Tam et al. (2015)
9 more

3 mentions without citation

Defense Peptides From the α-Hairpinin Family Are Components of Plant Innate Immunity.
Slavokhotova et al. (2020)
2 more