› 2l4m

Solution NMR

Solution structure of the Zbeta domain of human DAI and its binding modes to B- and Z-DNA

Released:
DOI: 10.2210/pdb2l4m/pdb
PDB entry 2l4m coloured by chain, ensemble of 20 models, front view.
PDB entry 2l4m coloured by chain, ensemble of 20 models, side view.
PDB entry 2l4m coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNA
Kim K, Khayrutdinov B, Lee C-K, Cheong H-K, Kang S, Park H, Lee S, Kim Y-G, Jee J-G, Rich A, Kim KK, Jeon YH
Proc. Natl. Acad. Sci. U.S.A. (2011)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190508 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Z-DNA-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 8.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H171 (Residues: 103-166; Coverage: 15%)
Gene names: C20orf183, DLM1, ZBP1
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Viral modulation of programmed necrosis.
Kaiser et al. (2013)
8 more

3 mentions without citation

Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs.
Kim et al. (2011)
2 more