› 2l7t

Solution NMR

Solution structure of the MFS-bound Sans CEN2 peptide

Released:
DOI: 10.2210/pdb2l7t/pdb
PDB entry 2l7t coloured by chain, ensemble of 10 models, front view.
PDB entry 2l7t coloured by chain, ensemble of 10 models, side view.
PDB entry 2l7t coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargo.
Wu L, Pan L, Wei Z, Zhang M
Science 331 757-60 (2011)
PMID: 21311020

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175402 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
pre-mRNA splicing regulator USH1G Chain: A
Molecule details ›
Chain: A
Length: 11 amino acids
Theoretical weight: 1.32 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q495M9 (Residues: 370-380; Coverage: 2%)
Gene names: SANS, USH1G

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

25 review citations

Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.
Mathur et al. (2015)
24 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)