› 2l7x

Solution NMR

Crimean Congo Hemorrhagic Fever Gn zinc finger

Released:
DOI: 10.2210/pdb2l7x/pdb
PDB entry 2l7x coloured by chain, front view.
PDB entry 2l7x coloured by chain, side view.
PDB entry 2l7x coloured by chain, top view.
Source organism: Orthonairovirus haemorrhagiae
Primary publication:
Structural characterization of the Crimean-Congo hemorrhagic fever virus Gn tail provides insight into virus assembly.
Estrada DF, De Guzman RN
J Biol Chem 286 21678-86 (2011)
PMID: 21507948

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.94 KDa
Source organism: Orthonairovirus haemorrhagiae
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q70UR3 (Residues: 734-810; Coverage: 5%)
Gene name: GPC
Sequence domains: Nairovirus NSm
Structure domains: Helicase, Ruva Protein; domain 3

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 38%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

Quick links

Citations

11 review citations

Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity.
Bente et al. (2013)
10 more

4 mentions without citation

Structural characterization of the Crimean-Congo hemorrhagic fever virus Gn tail provides insight into virus assembly.
Estrada et al. (2011)
3 more