› 2l7z

Solution NMR

NMR Structure of A13 homedomain

Released:
DOI: 10.2210/pdb2l7z/pdb
PDB entry 2l7z coloured by chain, ensemble of 15 models, front view.
PDB entry 2l7z coloured by chain, ensemble of 15 models, side view.
PDB entry 2l7z coloured by chain, ensemble of 15 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Zhang Y, Larsen CA, Stadler HS, Ames JB
PLoS One 6 e23069 (2011)
PMID: 21829694

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151974 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein Hox-A13 Chain: A
Molecule details ›
Chain: A
Length: 73 amino acids
Theoretical weight: 8.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P31271 (Residues: 322-388; Coverage: 17%)
Gene names: HOX1J, HOXA13
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 74%
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

1 review citation

Roles for major histocompatibility complex glycosylation in immune function.
Ryan et al. (2012)
16 other articles

6 mentions without citation

Trinucleotide repeats: a structural perspective.
Almeida et al. (2013)
5 more