› 2l8i

Solution NMR

A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA duplex

Released:
DOI: 10.2210/pdb2l8i/pdb
PDB entry 2l8i coloured by chain, ensemble of 11 models, front view.
PDB entry 2l8i coloured by chain, ensemble of 11 models, side view.
PDB entry 2l8i coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Structure and dynamics of triazole-linked DNA: biocompatibility explained.
Dallmann A, El-Sagheer AH, Dehmel L, Mügge C, Griesinger C, Ernsting NP, Brown T
Chemistry 17 14714-7 (2011)
PMID: 22131102

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115525 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3') Chain: A
Molecule details ›
Chain: A
Length: 13 nucleotides
Theoretical weight: 3.98 KDa
Source organism: Synthetic construct
Expression system: Not provided
DNA (5'-D(*CP*GP*AP*CP*G*(2L8)P*TP*GP*CP*AP*GP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.97 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 55%
Refinement method: torsion angle dynamics
Expression system: Not provided

Quick links

Citations

5 review citations

Click nucleic acid ligation: applications in biology and nanotechnology.
El-Sagheer et al. (2012)
4 more