› 2ld4

Solution NMR

Solution structure of the N-terminal domain of human anamorsin

Released:
DOI: 10.2210/pdb2ld4/pdb
PDB entry 2ld4 coloured by chain, ensemble of 30 models, front view.
PDB entry 2ld4 coloured by chain, ensemble of 30 models, side view.
PDB entry 2ld4 coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
Anamorsin is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery.
Banci L, Bertini I, Ciofi-Baffoni S, Boscaro F, Chatzi A, Mikolajczyk M, Tokatlidis K, Winkelmann J
Chem Biol 18 794-804 (2011)
PMID: 21700214

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179603 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anamorsin Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q6FI81 (Residues: 1-172; Coverage: 55%)
Gene names: CIAPIN1, CUA001, PRO0915
Sequence domains: Anamorsin, N-terminal
Structure domains: Vaccinia Virus protein VP39

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

The role of mitochondria and the CIA machinery in the maturation of cytosolic and nuclear iron-sulfur proteins.
Lill et al. (2015)
12 more

2 mentions without citation

Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.
Banci et al. (2013)
1 more