2lf7

Solution NMR

Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-161294 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor ETV6 Chain: A
Molecule details ›
Chain: A
Length: 106 amino acids
Theoretical weight: 13.06 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P97360 (Residues: 335-436; Coverage: 21%)
Gene names: Etv6, Tel, Tel1
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)