› 2lfh

Solution NMR

Solution NMR Structure of the Helix-loop-Helix Domain of Human ID3 Protein, Northeast Structural Genomics Consortium Target HR3111A

Released:
DOI: 10.2210/pdb2lfh/pdb
PDB entry 2lfh coloured by chain, ensemble of 20 models, front view.
PDB entry 2lfh coloured by chain, ensemble of 20 models, side view.
PDB entry 2lfh coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Eletsky A, Wang D, Kohan E, Janjua H, Acton TB, Xiao R, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169724 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA-binding protein inhibitor ID-3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 68 amino acids
Theoretical weight: 7.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q02535 (Residues: 29-83; Coverage: 46%)
Gene names: 1R21, BHLHB25, HEIR1, ID3
Sequence domains: Helix-loop-helix DNA-binding domain
Structure domains: Helix-loop-helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 44%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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