› 2lgq

Solution NMR

Human C30S/C59S-Cox17 mutant

Released:
DOI: 10.2210/pdb2lgq/pdb
PDB entry 2lgq coloured by chain, ensemble of 20 models, front view.
PDB entry 2lgq coloured by chain, ensemble of 20 models, side view.
PDB entry 2lgq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Functional role of two interhelical disulfide bonds in human Cox17 protein from a structural perspective.
Banci L, Bertini I, Cefaro C, Ciofi-Baffoni S, Gallo A
J Biol Chem 286 34382-90 (2011)
PMID: 21816817

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171903 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c oxidase copper chaperone Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14061 (Residues: 1-63; Coverage: 100%)
Gene name: COX17
Sequence domains: Cytochrome C oxidase copper chaperone (COX17)
Structure domains: CytochromE C oxidase copper chaperone

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 64%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells.
Geldon et al. (2021)
3 more

2 mentions without citation

Functional role of two interhelical disulfide bonds in human Cox17 protein from a structural perspective.
Banci et al. (2011)
1 more