› 2lke

Solution NMR

Structures and Interaction Analyses of the Integrin Alpha-M Beta-2 Cytoplasmic Tails

Released:
DOI: 10.2210/pdb2lke/pdb
PDB entry 2lke coloured by chain, ensemble of 20 models, front view.
PDB entry 2lke coloured by chain, ensemble of 20 models, side view.
PDB entry 2lke coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structures and interaction analyses of integrin αMβ2 cytoplasmic tails.
Chua GL, Tang XY, Amalraj M, Tan SM, Bhattacharjya S
J Biol Chem 286 43842-43854 (2011)
PMID: 22052909

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-M Chain: A
Molecule details ›
Chain: A
Length: 24 amino acids
Theoretical weight: 2.7 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P11215 (Residues: 1129-1152; Coverage: 2%)
Gene names: CD11B, CR3A, ITGAM
Sequence domains: Integrin alpha cytoplasmic region

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 50%
Expression system: Not provided

Quick links

Citations

3 review citations

The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.
Tan SM. (2012)
2 more

2 mentions without citation

Structural biology of complement receptors.
Santos-López et al. (2023)
1 more