› 2lpw

Solution NMR

human CEB25 minisatellite G-quadruplex

Released:
DOI: 10.2210/pdb2lpw/pdb
PDB entry 2lpw coloured by chain, ensemble of 10 models, front view.
PDB entry 2lpw coloured by chain, ensemble of 10 models, side view.
PDB entry 2lpw coloured by chain, ensemble of 10 models, top view.
Source organism: Synthetic construct
Primary publication:
Formation of pearl-necklace monomorphic G-quadruplexes in the human CEB25 minisatellite.
Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny JL, Phan AT
J Am Chem Soc 134 5807-16 (2012)
PMID: 22376028

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115558 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (26-MER) Chain: A
Molecule details ›
Chain: A
Length: 26 nucleotides
Theoretical weight: 8.28 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 51%
Refinement method: simulated annealing, molecular dynamics
Expression system: Not provided

Quick links

Citations

10 review citations

G4-associated human diseases.
Maizels N. (2015)
9 more

9 mentions without citation

G-quadruplexes in viruses: function and potential therapeutic applications.
Métifiot et al. (2014)
8 more