› 2lqy

Solution NMR

Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.

Released:
DOI: 10.2210/pdb2lqy/pdb
PDB entry 2lqy coloured by chain, ensemble of 20 models, front view.
PDB entry 2lqy coloured by chain, ensemble of 20 models, side view.
PDB entry 2lqy coloured by chain, ensemble of 20 models, top view.
Source organism: Human alphaherpesvirus 1
Primary publication:
Structure and orientation of the gH625-644 membrane interacting region of herpes simplex virus type 1 in a membrane mimetic system.
Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C
Biochemistry 51 3121-8 (2012)
PMID: 22397737

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139058 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Envelope glycoprotein H Chain: A
Molecule details ›
Chain: A
Length: 20 amino acids
Theoretical weight: 2.3 KDa
Source organism: Human alphaherpesvirus 1
Expression system: Not provided
UniProt:
  • Canonical: P06477 (Residues: 625-644; Coverage: 2%)
Gene names: UL22, gH

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 37%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

6 review citations

Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity.
Kalafatovic et al. (2017)
5 more

1 mention without citation

Association Mechanism of Peptide-Coated Metal Nanoparticles with Model Membranes: A Coarse-Grained Study.
Franco-Ulloa et al. (2021)