› 2lr6

Solution NMR

NMR structure of a LINE-1 type transposase domain-containing protein 1 (L1TD1) from Homo sapiens

Released:
DOI: 10.2210/pdb2lr6/pdb
PDB entry 2lr6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lr6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lr6 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Serrano P, Geralt M, Mohanty B, Wuthrich K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology, Partnership for Stem Cell Biology (STEMCELL)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178308 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
LINE-1 type transposase domain-containing protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 88 amino acids
Theoretical weight: 9.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5T7N2 (Residues: 235-321; Coverage: 10%)
Gene names: ECAT11, L1TD1
Sequence domains: L1 transposable element dsRBD-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 41%
Refinement method: simulated annealing
Expression system: Escherichia coli

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