› 2lr8

Solution NMR

Solution NMR Structure of CASP8-associated protein 2 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8150A

Released:
DOI: 10.2210/pdb2lr8/pdb
PDB entry 2lr8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lr8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lr8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Pulavarti S, Sathyamoorthy B, Eletsky A, Sukumaran DK, Lee D, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193851 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CASP8-associated protein 2 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UKL3 (Residues: 1916-1982; Coverage: 3%)
Gene names: CASP8AP2, FLASH, KIAA1315, RIP25
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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