Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA repair protein REV1 and DNA polymerase kappa (preferred)
PDBe Complex ID:
PDB-CPX-187636 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA repair protein REV1
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA repair protein REV1 C-terminal domain
Structure domains: DNA repair protein Rev1, C-terminal domain
Length: 119 amino acids
Theoretical weight: 13.27 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q920Q2 (Residues: 1135-1249; Coverage: 9%)
Sequence domains: DNA repair protein REV1 C-terminal domain
Structure domains: DNA repair protein Rev1, C-terminal domain
DNA polymerase kappa
Molecule details ›
Chain: B
Length: 25 amino acids
Theoretical weight: 2.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Length: 25 amino acids
Theoretical weight: 2.99 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical: Q9QUG2 (Residues: 560-582; Coverage: 3%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
87%
Refinement method:
simulated annealing
Expression system: Escherichia coli
