› 2lu0

Solution NMR

NMR solution structure of the kappa-zeta region of S.cerevisiae group II intron ai5(gamma)

Released:
DOI: 10.2210/pdb2lu0/pdb
PDB entry 2lu0 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lu0 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lu0 coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
The structural stabilization of the κ three-way junction by Mg(II) represents the first step in the folding of a group II intron.
Donghi D, Pechlaner M, Finazzo C, Knobloch B, Sigel RK
Nucleic Acids Res 41 2489-504 (2013)
PMID: 23275550

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196475 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (49-MER) Chain: A
Molecule details ›
Chain: A
Length: 49 nucleotides
Theoretical weight: 15.8 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 65%
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Not provided

Quick links

Citations

2 review citations

Structural Insights into the Mechanism of Group II Intron Splicing.
Zhao et al. (2017)
1 more

6 mentions without citation

Targeting RNA with Small Molecules To Capture Opportunities at the Intersection of Chemistry, Biology, and Medicine.
Disney MD. (2019)
5 more