› 2lv7

Solution NMR

Solution structure of Ca2+-bound CaBP7 N-terminal doman

Released:
DOI: 10.2210/pdb2lv7/pdb
PDB entry 2lv7 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lv7 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lv7 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution NMR structure of the Ca2+-bound N-terminal domain of CaBP7: a regulator of golgi trafficking.
McCue HV, Patel P, Herbert AP, Lian LY, Burgoyne RD, Haynes LP
J Biol Chem 287 38231-43 (2012)
PMID: 22989873

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183207 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-binding protein 7 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86V35 (Residues: 1-100; Coverage: 47%)
Gene names: CABP7, CALN2
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Calcium Sensors in Neuronal Function and Dysfunction.
Burgoyne et al. (2019)
2 other articles

4 mentions without citation

Sense and specificity in neuronal calcium signalling.
Burgoyne et al. (2015)
3 more