› 2lvb

Solution NMR

Solution NMR Structure DE NOVO DESIGNED PFK fold PROTEIN, Northeast Structural Genomics Consortium (NESG) Target OR250

Released:
DOI: 10.2210/pdb2lvb/pdb
PDB entry 2lvb coloured by chain, ensemble of 20 models, front view.
PDB entry 2lvb coloured by chain, ensemble of 20 models, side view.
PDB entry 2lvb coloured by chain, ensemble of 20 models, top view.
Source organism: synthetic construct
Primary publication:
Principles for designing ideal protein structures.
Koga N, Tatsumi-Koga R, Liu G, Xiao R, Acton TB, Montelione GT, Baker D
Nature 491 222-7 (2012)
PMID: 23135467

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162930 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DE NOVO DESIGNED PFK fold PROTEIN Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.67 KDa
Source organism: synthetic construct
Expression system: Escherichia coli
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: distance geometry, simulated annealing, torsion angle dynamics, molecular dynamics
Expression system: Escherichia coli

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Citations

60 review citations

The coming of age of de novo protein design.
Huang et al. (2016)
59 more

4 mentions without citation

Principles for designing ideal protein structures.
Koga et al. (2012)
3 more