› 2lw4

Solution NMR

Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B

Released:
DOI: 10.2210/pdb2lw4/pdb
PDB entry 2lw4 coloured by chain, ensemble of 20 models, front view.
PDB entry 2lw4 coloured by chain, ensemble of 20 models, side view.
PDB entry 2lw4 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Eletsky A, Wang D, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172326 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription elongation factor A protein 2 Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15560 (Residues: 130-239; Coverage: 37%)
Gene name: TCEA2
Sequence domains: Transcription factor S-II (TFIIS), central domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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