› 2lwh

Solution NMR

NMR Structure of the Self-Complementary 10 mer DNA Duplex 5'-GGATATATCC-3' in Complex with Netropsin

Released:
DOI: 10.2210/pdb2lwh/pdb
PDB entry 2lwh coloured by chain, ensemble of 11 models, front view.
PDB entry 2lwh coloured by chain, ensemble of 11 models, side view.
PDB entry 2lwh coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Molecular basis for sequence-dependent induced DNA bending.
Rettig M, Germann MW, Wang S, Wilson WD
Chembiochem 14 323-31 (2013)
PMID: 23355266

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115568 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*GP*GP*AP*TP*AP*TP*AP*TP*CP*C)-3') Chains: 1, 2
Molecule details ›
Chains: 1, 2
Length: 10 nucleotides
Theoretical weight: 3.04 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NT 1 x NT
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 40%
Refinement method: simulated annealing, molecular dynamics
Expression system: Not provided

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Citations

2 review citations

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: synthesis, photophysics and applications.
Bood et al. (2018)
1 more

4 mentions without citation

A Dual-Specific Targeting Approach Based on the Simultaneous Recognition of Duplex and Quadruplex Motifs.
Nguyen et al. (2017)
3 more