› 2lxq

Solution NMR

Monomeric PilE G-Quadruplex DNA from Neisseria Gonorrhoeae

Released:
DOI: 10.2210/pdb2lxq/pdb
PDB entry 2lxq coloured by chain, ensemble of 12 models, front view.
PDB entry 2lxq coloured by chain, ensemble of 12 models, side view.
PDB entry 2lxq coloured by chain, ensemble of 12 models, top view.
Source organism: Synthetic construct
Primary publication:
RecA-binding pilE G4 sequence essential for pilin antigenic variation forms monomeric and 5' end-stacked dimeric parallel G-quadruplexes.
Kuryavyi V, Cahoon LA, Seifert HS, Patel DJ
Structure 20 2090-102 (2012)
PMID: 23085077

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115572 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*TP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*T)-3') Chain: A
Molecule details ›
Chain: A
Length: 22 nucleotides
Theoretical weight: 7 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 39%
Refinement method: torsion angle dynamics, molecular dynamics, matrix relaxation
Expression system: Not provided

Quick links

Citations

13 review citations

G4-associated human diseases.
Maizels N. (2015)
12 more

4 mentions without citation

ALU non-B-DNA conformations, flipons, binary codes and evolution.
Herbert A. (2020)
3 more