› 2lye

Solution NMR

High resolution NMR solution structure of a symmetrical theta-defensin, BTD-2

Released:
DOI: 10.2210/pdb2lye/pdb
PDB entry 2lye coloured by chain, ensemble of 20 models, front view.
PDB entry 2lye coloured by chain, ensemble of 20 models, side view.
PDB entry 2lye coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Structural characterization of the cyclic cystine ladder motif of θ-defensins.
Conibear AC, Rosengren KJ, Harvey PJ, Craik DJ
Biochemistry 51 9718-26 (2012)
PMID: 23148585

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162939 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BTD-2 Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.09 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 73%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Not provided

Quick links

Citations

10 review citations

New Modalities for Challenging Targets in Drug Discovery.
Valeur et al. (2017)
9 more

3 mentions without citation

The chemistry and biology of theta defensins.
Conibear et al. (2014)
2 more