› 2m13

Solution NMR

The ZZ domain of cytoplasmic polyadenylation element binding protein 1 (CPEB1)

Released:
DOI: 10.2210/pdb2m13/pdb
PDB entry 2m13 coloured by chain, ensemble of 20 models, front view.
PDB entry 2m13 coloured by chain, ensemble of 20 models, side view.
PDB entry 2m13 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The C-terminal region of cytoplasmic polyadenylation element binding protein is a ZZ domain with potential for protein-protein interactions.
Merkel DJ, Wells SB, Hilburn BC, Elazzouzi F, Pérez-Alvarado GC, Lee BM
J Mol Biol 425 2015-2026 (2013)
PMID: 23500490

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189855 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytoplasmic polyadenylation element-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BZB8 (Residues: 504-566; Coverage: 11%)
Gene names: CPEB, CPEB1
Sequence domains: Cytoplasmic polyadenylation element-binding protein ZZ domain
Structure domains: Cytoplasmic polyadenylation element-binding protein, ZZ domain

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The translational regulation of maternal mRNAs in time and space.
Winata et al. (2018)
15 other articles

2 mentions without citation

Structure and function of pre-mRNA 5'-end capping quality control and 3'-end processing.
Jurado et al. (2014)
1 more