› 2m2i

Solution NMR

NMR solution structure of BRCT domain of yeast REV1

Released:
DOI: 10.2210/pdb2m2i/pdb
PDB entry 2m2i coloured by chain, ensemble of 20 models, front view.
PDB entry 2m2i coloured by chain, ensemble of 20 models, side view.
PDB entry 2m2i coloured by chain, ensemble of 20 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain.
Pustovalova Y, Maciejewski MW, Korzhnev DM
J Mol Biol 425 3091-105 (2013)
PMID: 23747975

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146299 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair protein REV1 Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.79 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P12689 (Residues: 158-251; Coverage: 10%)
Gene names: O6339, REV1, YOR346W
Sequence domains: BRCT domain, a BRCA1 C-terminus domain
Structure domains: BRCT domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

12 review citations

Lesion Bypass and the Reactivation of Stalled Replication Forks.
Marians KJ. (2018)
11 more

2 mentions without citation

An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η.
Yang W. (2014)
1 more