› 2m4g

Solution NMR

Solution structure of the Core Domain (11-85) of the Murine Norovirus VPg protein

Released:
DOI: 10.2210/pdb2m4g/pdb
PDB entry 2m4g coloured by chain, ensemble of 20 models, front view.
PDB entry 2m4g coloured by chain, ensemble of 20 models, side view.
PDB entry 2m4g coloured by chain, ensemble of 20 models, top view.
Source organism: Murine norovirus 1
Primary publication:
Structures of the compact helical core domains of feline calicivirus and murine norovirus VPg proteins.
Leen EN, Kwok KY, Birtley JR, Simpson PJ, Subba-Reddy CV, Chaudhry Y, Sosnovtsev SV, Green KY, Prater SN, Tong M, Young JC, Chung LM, Marchant J, Roberts LO, Kao CC, Matthews S, Goodfellow IG, Curry S
J Virol 87 5318-30 (2013)
PMID: 23487472

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Viral genome-linked protein Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.88 KDa
Source organism: Murine norovirus 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q80J95 (Residues: 881-955; Coverage: 4%)
Gene name: ORF1
Structure domains: Arc Repressor Mutant, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Norovirus gene expression and replication.
Thorne et al. (2014)
9 more

4 mentions without citation

Translational Control during Calicivirus Infection.
Royall et al. (2016)
3 more