› 2m5h

Solution NMR

NMR structure note: solution structure of monomeric human FAM96A

Released:
DOI: 10.2210/pdb2m5h/pdb
PDB entry 2m5h coloured by chain, ensemble of 20 models, front view.
PDB entry 2m5h coloured by chain, ensemble of 20 models, side view.
PDB entry 2m5h coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of monomeric human FAM96A.
Ouyang B, Wang L, Wan S, Luo Y, Wang L, Lin J, Xia B
J Biomol NMR 56 387-92 (2013)
PMID: 23793605

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190628 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytosolic iron-sulfur assembly component 2A Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 16.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H5X1 (Residues: 28-160; Coverage: 83%)
Gene names: CIA2A, CIAO2A, FAM96A
Sequence domains: Iron-sulfur cluster assembly protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

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Citations

4 review citations

Emerging critical roles of Fe-S clusters in DNA replication and repair.
Fuss et al. (2015)
3 more

1 mention without citation

Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo.
Tripathi et al. (2022)