› 2m6y

Solution NMR

The solution structure of the J-domain of human DnaJA1

Released:
DOI: 10.2210/pdb2m6y/pdb
PDB entry 2m6y coloured by chain, ensemble of 20 models, front view.
PDB entry 2m6y coloured by chain, ensemble of 20 models, side view.
PDB entry 2m6y coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer.
Stark JL, Mehla K, Chaika N, Acton TB, Xiao R, Singh PK, Montelione GT, Powers R
Biochemistry 53 1360-72 (2014)
PMID: 24512202

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152070 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DnaJ homolog subfamily A member 1 Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 9.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P31689 (Residues: 1-67; Coverage: 17%)
Gene names: DNAJ2, DNAJA1, HDJ2, HSJ2, HSPF4
Sequence domains: DnaJ domain
Structure domains: DnaJ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: distance geometry, torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Dynamical Structures of Hsp70 and Hsp70-Hsp40 Complexes.
Alderson et al. (2016)
4 more

9 mentions without citation

The Role of Co-chaperones in Synaptic Proteostasis and Neurodegenerative Disease.
Gorenberg et al. (2017)
8 more