› 2m7s

Solution NMR

NMR structure of RNA recognition motif 2 (RRM2) of Homo sapiens splicing factor, arginine/serine-rich 1

Released:
DOI: 10.2210/pdb2m7s/pdb
PDB entry 2m7s coloured by chain, ensemble of 20 models, front view.
PDB entry 2m7s coloured by chain, ensemble of 20 models, side view.
PDB entry 2m7s coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Dutta SK, Serrano P, Geralt M, Wuthrich K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170572 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/arginine-rich splicing factor 1 Chain: A
Molecule details ›
Chain: A
Length: 90 amino acids
Theoretical weight: 10.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q07955 (Residues: 106-195; Coverage: 36%)
Gene names: ASF, OK/SW-cl.3, SF2, SF2P33, SFRS1, SRSF1
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21

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