› 2mae

Solution NMR

Transmembrane-cytosolic part of Trop2 explored by NMR and Molecular Dynamics

Released:
DOI: 10.2210/pdb2mae/pdb
PDB entry 2mae coloured by chain, ensemble of 20 models, front view.
PDB entry 2mae coloured by chain, ensemble of 20 models, side view.
PDB entry 2mae coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Vidmar T, Pavi M, Ilc G, Plavec J, Lenari B

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140740 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor-associated calcium signal transducer 2 Chain: A
Molecule details ›
Chain: A
Length: 26 amino acids
Theoretical weight: 3.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09758 (Residues: 298-323; Coverage: 9%)
Gene names: GA733-1, M1S1, TACSTD2, TROP2

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 1 x SEP

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: molecular dynamics
Expression system: Not provided

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