Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171771 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Stromal interaction molecule 1
Molecule details ›
Chains: A, C
Length: 82 amino acids
Theoretical weight: 9.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: STIM1 Orai1-activating region
Length: 82 amino acids
Theoretical weight: 9.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q13586 (Residues: 312-387; Coverage: 12%)
Sequence domains: STIM1 Orai1-activating region
Calcium release-activated calcium channel protein 1
Molecule details ›
Chains: B, D
Length: 23 amino acids
Theoretical weight: 2.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 23 amino acids
Theoretical weight: 2.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q96D31 (Residues: 272-292; Coverage: 7%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
42%
Refinement method:
simulated annealing
Expression system: Escherichia coli
