› 2mar

Solution NMR

Solution structure of Ani s 5 Anisakis simplex allergen

Released:
DOI: 10.2210/pdb2mar/pdb
PDB entry 2mar coloured by chain, ensemble of 20 models, front view.
PDB entry 2mar coloured by chain, ensemble of 20 models, side view.
PDB entry 2mar coloured by chain, ensemble of 20 models, top view.
Source organism: Anisakis simplex
Primary publication:
Relationships between IgE/IgG4 epitopes, structure and function in Anisakis simplex Ani s 5, a member of the SXP/RAL-2 protein family.
García-Mayoral MF, Treviño MA, Pérez-Piñar T, Caballero ML, Knaute T, Umpierrez A, Bruix M, Rodríguez-Pérez R
PLoS Negl Trop Dis 8 e2735 (2014)
PMID: 24603892

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106612 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SXP/RAL-2 family protein Ani s 5 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 14.76 KDa
Source organism: Anisakis simplex
Expression system: Escherichia coli
UniProt:
  • Canonical: A1IKL2 (Residues: 19-152; Coverage: 100%)
Sequence domains: SXP/RAL-2 family protein Ani s 5-like, metal-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 77%
Refinement method: torsion angle dynamics, energy minimization
Expression system: Escherichia coli

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Citations

1 review citation

Advancing a Human Onchocerciasis Vaccine From Antigen Discovery to Efficacy Studies Against Natural Infection of Cattle With Onchocerca ochengi.
Zhan et al. (2022)
5 other articles

7 mentions without citation

Tsg101, an inactive homologue of ubiquitin ligase e2, interacts specifically with human immunodeficiency virus type 2 gag polyprotein and results in increased levels of ubiquitinated gag.
Myers et al. (2002)
6 more