› 2mbf

Solution NMR

Solution structure of the forkhead domain of Brugia malayi DAF-16a

Released:
DOI: 10.2210/pdb2mbf/pdb
PDB entry 2mbf coloured by chain, ensemble of 20 models, front view.
PDB entry 2mbf coloured by chain, ensemble of 20 models, side view.
PDB entry 2mbf coloured by chain, ensemble of 20 models, top view.
Source organism: Brugia malayi
Primary publication:
The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a.
Casper SK, Schoeller SJ, Zgoba DM, Phillips AJ, Morien TJ, Chaffee GR, Sackett PC, Peterson FC, Crossgrove K, Veldkamp CT
Proteins 82 3490-6 (2014)
PMID: 25297652

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fork head domain containing protein Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 11.67 KDa
Source organism: Brugia malayi
Expression system: Escherichia coli
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

3 citation in other articles

A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-β/Sma/Mab pathway.
Goszczynski et al. (2016)
2 more

1 mention without citation

The solution structure of the forkhead box-O DNA binding domain of Brugia malayi DAF-16a.
Casper et al. (2014)