› 2md3

Solution NMR

Fragment based approach and binding behavior of LFampinB with Lipopolysaccharide:biophysical aspects

Released:
DOI: 10.2210/pdb2md3/pdb
PDB entry 2md3 coloured by chain, ensemble of 10 models, front view.
PDB entry 2md3 coloured by chain, ensemble of 10 models, side view.
PDB entry 2md3 coloured by chain, ensemble of 10 models, top view.
Source organism: Bos taurus
Primary publication:
Sequence context induced antimicrobial activity: insight into lipopolysaccharide permeabilization.
Ghosh A, Datta A, Jana J, Kar RK, Chatterjee C, Chatterjee S, Bhunia A
Mol Biosyst 10 1596-612 (2014)
PMID: 24714742

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 8 amino acids
Theoretical weight: 968 Da
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P24627 (Residues: 296-303; Coverage: 1%)
Gene name: LTF

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 28%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Not provided

Quick links

Citations

13 citation in other articles

D-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions.
Di Grazia et al. (2015)
12 more

3 mentions without citation

PI3K/Akt signalling is required for the attachment and spreading, and growth in vivo of metastatic scirrhous gastric carcinoma.
Matsuoka et al. (2012)
2 more