› 2mem

Solution NMR

Solution NMR structure of SLED domain of Scml2

Released:
DOI: 10.2210/pdb2mem/pdb
PDB entry 2mem coloured by chain, ensemble of 20 models, front view.
PDB entry 2mem coloured by chain, ensemble of 20 models, side view.
PDB entry 2mem coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution NMR structure of the DNA-binding domain from Scml2 (sex comb on midleg-like 2).
Bezsonova I
J Biol Chem 289 15739-49 (2014)
PMID: 24727478

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194074 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sex comb on midleg-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 13.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UQR0 (Residues: 354-468; Coverage: 16%)
Gene name: SCML2
Sequence domains: SLED domain
Structure domains: SLED domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 87%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

6 citation in other articles

Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis.
Luo et al. (2015)
5 more

1 mention without citation

Solution NMR structure of the DNA-binding domain from Scml2 (sex comb on midleg-like 2).
Bezsonova I. (2014)