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Solution NMR

Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A

Released:
DOI: 10.2210/pdb2mio/pdb
PDB entry 2mio coloured by chain, ensemble of 20 models, front view.
PDB entry 2mio coloured by chain, ensemble of 20 models, side view.
PDB entry 2mio coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Xu X, Eletsky A, Pulavarti SVSRK, Wang H, Janjua H, Xiao R, Everett JK, Sukumaran DK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-106543 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GTPase-activating protein 10 Chain: A
Molecule details ›
Chain: A
Length: 70 amino acids
Theoretical weight: 8.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A1A4S6 (Residues: 728-786; Coverage: 8%)
Gene names: ARHGAP10, GRAF2
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 93%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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