› 2mj7

Solution NMR

Solution NMR structure of beta-adaptin appendage domain of human adaptor protein complex 4 subunit beta, Northeast Structural Genomics Consortium (NESG) Target HR8998C

Released:
DOI: 10.2210/pdb2mj7/pdb
PDB entry 2mj7 coloured by chain, ensemble of 20 models, front view.
PDB entry 2mj7 coloured by chain, ensemble of 20 models, side view.
PDB entry 2mj7 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Eletsky A, Rotshteyn DJ, Pederson K, Shastry R, Maglaqui M, Janjua H, Xiao R, Everett JK, Montelione GT, Prestegard JH, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195351 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AP-4 complex subunit beta-1 Chain: A
Molecule details ›
Chain: A
Length: 141 amino acids
Theoretical weight: 16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y6B7 (Residues: 610-739; Coverage: 18%)
Gene name: AP4B1
Sequence domains: Beta2-adaptin appendage, C-terminal sub-domain
Structure domains: TATA-Binding Protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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