› 2mjp

X-ray diffraction
2.2Å resolution

STRUCTURE-BASED IDENTIFICATION OF THE BIOCHEMICAL FUNCTION OF A HYPOTHETICAL PROTEIN FROM METHANOCOCCUS JANNASCHII:MJ0226

Released:
DOI: 10.2210/pdb2mjp/pdb
PDB entry 2mjp coloured by chain, front view.
PDB entry 2mjp coloured by chain, side view.
PDB entry 2mjp coloured by chain, top view.
Source organism: Methanocaldococcus jannaschii
Primary publication:
Structure-based identification of a novel NTPase from Methanococcus jannaschii.
Hwang KY, Chung JH, Kim SH, Han YS, Cho Y
Nat Struct Biol 6 691-6 (1999)
PMID: 10404228

Function and Biology Details

Reaction catalysed: 
ITP + H(2)O = IMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dITP/XTP pyrophosphatase Chains: A, B
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 22.23 KDa
Source organism: Methanocaldococcus jannaschii
UniProt:
  • Canonical: Q57679 (Residues: 1-185; Coverage: 100%)
Gene name: MJ0226
Sequence domains: Ham1 family
Structure domains: Maf protein

Ligands and Environments

1 bound ligand:
Ligand ANP 1 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 44.36Å b: 72.13Å c: 140.53Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.204 0.259

Quick links

Citations

16 review citations

Search and discovery strategies for biotechnology: the paradigm shift.
Bull et al. (2000)
15 more

6 mentions without citation

'Conserved hypothetical' proteins: prioritization of targets for experimental study.
Galperin et al. (2004)
5 more