› 2mjq

Solution NMR

Structure of antimicrobial peptide anoplin in DPC micelles

Released:
DOI: 10.2210/pdb2mjq/pdb
PDB entry 2mjq coloured by chain, ensemble of 20 models, front view.
PDB entry 2mjq coloured by chain, ensemble of 20 models, side view.
PDB entry 2mjq coloured by chain, ensemble of 20 models, top view.
Source organism: Anoplius samariensis
Primary publication:
Rational design of alpha-helical antimicrobial peptides: do's and don'ts.
Uggerhøj LE, Poulsen TJ, Munk JK, Fredborg M, Sondergaard TE, Frimodt-Moller N, Hansen PR, Wimmer R
Chembiochem 16 242-53 (2015)
PMID: 25530580

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142848 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anoplin Chain: A
Molecule details ›
Chain: A
Length: 11 amino acids
Theoretical weight: 1.16 KDa
Source organism: Anoplius samariensis
Expression system: Not provided
UniProt:
  • Canonical: P0C005 (Residues: 1-10; Coverage: 100%)

Ligands and Environments

2 bound ligands:
Ligand UNX 1 x UNX
Ligand DPV 65 x DPV
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 77%
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

11 review citations

Peptides with Dual Antimicrobial and Anticancer Activities.
Felício et al. (2017)
10 more

1 mention without citation

Antimicrobial peptides: An annotated selection of World Wide Web sites relevant to the topics in microbial biotechnology.
Wackett LP. (2019)