› 2mju

Solution NMR

Solution structure of a C terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)

Released:
DOI: 10.2210/pdb2mju/pdb
PDB entry 2mju coloured by chain, ensemble of 20 models, front view.
PDB entry 2mju coloured by chain, ensemble of 20 models, side view.
PDB entry 2mju coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB).
Joshi A, Esteve V, Buckroyd AN, Blatter M, Allain FH, Curry S
PeerJ 2 e305 (2014)
PMID: 24688880

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193841 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Polypyrimidine tract-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 22.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UKA9 (Residues: 325-531; Coverage: 39%)
Gene names: NPTB, PTB, PTBLP, PTBP2
Sequence domains:
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 73%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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Citations

6 citation in other articles

The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein.
Blatter et al. (2015)
5 more

1 mention without citation

Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB).
Joshi et al. (2014)