› 2mkv

Solution NMR

Structure of the NA,K-ATPASE regulatory protein FXYD2b in micelles

Released:
DOI: 10.2210/pdb2mkv/pdb
PDB entry 2mkv coloured by chain, ensemble of 10 models, front view.
PDB entry 2mkv coloured by chain, ensemble of 10 models, side view.
PDB entry 2mkv coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the Na,K-ATPase regulatory protein FXYD2b in micelles: implications for membrane-water interfacial arginines.
Gong XM, Ding Y, Yu J, Yao Y, Marassi FM
Biochim Biophys Acta 1848 299-306 (2015)
PMID: 24794573

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157076 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sodium/potassium-transporting ATPase subunit gamma Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P54710 (Residues: 9-66; Coverage: 88%)
Gene names: ATP1C, ATP1G1, FXYD2
Sequence domains: ATP1G1/PLM/MAT8 family
Structure domains: Single helix bin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 49%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.
Chipot et al. (2018)
2 more

2 mentions without citation

FXYD proteins and sodium pump regulatory mechanisms.
Yap et al. (2021)
1 more