› 2mlh

Solution NMR

NMR Solution Structure of Opa60 from N. Gonorrhoeae in FC-12 Micelles

Released:
DOI: 10.2210/pdb2mlh/pdb
PDB entry 2mlh coloured by chain, ensemble of 20 models, front view.
PDB entry 2mlh coloured by chain, ensemble of 20 models, side view.
PDB entry 2mlh coloured by chain, ensemble of 20 models, top view.
Source organism: Neisseria gonorrhoeae
Primary publication:
Structure of the Neisserial outer membrane protein Opa₆₀: loop flexibility essential to receptor recognition and bacterial engulfment.
Fox DA, Larsson P, Lo RH, Kroncke BM, Kasson PM, Columbus L
J Am Chem Soc 136 9938-46 (2014)
PMID: 24813921

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170088 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Opacity protein opA60 Chain: A
Molecule details ›
Chain: A
Length: 238 amino acids
Theoretical weight: 27.12 KDa
Source organism: Neisseria gonorrhoeae
Expression system: Neisseria gonorrhoeae
UniProt:
  • Canonical: Q04884 (Residues: 1-238; Coverage: 100%)
Gene name: opaH
Sequence domains: Opacity family porin protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 30%
Refinement method: simulated annealing
Expression system: Neisseria gonorrhoeae

Quick links

Citations

5 review citations

Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies.
Chipot et al. (2018)
4 more

7 mentions without citation

CEACAM1 structure and function in immunity and its therapeutic implications.
Kim et al. (2019)
6 more