› 2mmm

Solution NMR

Solution structure of the mature form, GK cecropin-like peptide from Ae. aegypti mosquito

Released:
DOI: 10.2210/pdb2mmm/pdb
PDB entry 2mmm coloured by chain, ensemble of 20 models, front view.
PDB entry 2mmm coloured by chain, ensemble of 20 models, side view.
PDB entry 2mmm coloured by chain, ensemble of 20 models, top view.
Source organism: Aedes aegypti
Primary publication:
Aedesin: structure and antimicrobial activity against multidrug resistant bacterial strains.
Godreuil S, Leban N, Padilla A, Hamel R, Luplertlop N, Chauffour A, Vittecoq M, Hoh F, Thomas F, Sougakoff W, Lionne C, Yssel H, Missé D
PLoS One 9 e105441 (2014)
PMID: 25162372

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172641 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AAEL000598-PA Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 3.69 KDa
Source organism: Aedes aegypti
Expression system: Escherichia coli
UniProt:
  • Canonical: Q17NR1 (Residues: 24-59; Coverage: 100%)
Gene names: AAEL000598, CECD
Sequence domains: Cecropin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 66%
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

1 review citation

Application of Antibiotics/Antimicrobial Agents on Dental Caries.
Qiu et al. (2020)
5 other articles

3 mentions without citation

Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance.
Manniello et al. (2021)
2 more