› 2mnd

Solution NMR

Recognition complex of DNA d(CGACGCGTCG)2 with thiazotropsin B

Released:
DOI: 10.2210/pdb2mnd/pdb
PDB entry 2mnd coloured by chain, front view.
PDB entry 2mnd coloured by chain, side view.
PDB entry 2mnd coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Recognition of the DNA minor groove by thiazotropsin analogues.
Alniss HY, Salvia MV, Sadikov M, Golovchenko I, Anthony NG, Khalaf AI, MacKay SP, Suckling CJ, Parkinson JA
Chembiochem 15 1978-90 (2014)
PMID: 25045155

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115632 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*AP*CP*GP*CP*GP*TP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand 3BF 2 x 3BF
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 20%
Refinement method: molecular dynamics
Expression system: Not provided

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Citations

1 review citation

An overview of recent advances in duplex DNA recognition by small molecules.
Bhaduri et al. (2018)
7 other articles